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This is especially important considering the increasing use of these medications. The authors write that, to their knowledge, this is the first case detailing a patient developing this serious condition after starting tirzepatide for diabetes (in contrast to those treated with tirzepatide for weight loss)

Study treatments were administered in the morning with approximately 200 mL of water and a standardized breakfast under direct supervision by the study personnel

10.1038/s41588-018-0070-7 193 KwiatkowskiT

Moreover, it shields the skin from environmental stressors like pollution and UV radiation, which are notorious for inducing premature ageing and damage