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HGF gene therapy employing naked plasmids succeeds in preventing neuronal death in animal models of ALS (Sun et al., 2002) and PD (Koike et al., 2006, 2009) and induces analgesic effects in a neuropathic pain model (Nho et al., 2018)

However, the potential risks associated with reducing melanin levels, as well as the lack of long-term studies on glutathione's effects, suggest that caution is warranted

It confirms the platform has been reviewed against defined legal operation standards - though it doesn't guarantee clinical outcomes or future regulatory continuity

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