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Yes, several medical researches have shown that Semaglutide is effective in the management of weight gain in women with PCOS, including those who could not reduce their body weight via lifestyle modifications

Whereas in one study the administration of ghrelin (versus placebo) in the fasted state increased anticipatory responses, they did not find a significant correlation between plasma ghrelin levels and reward responses at individual sessions (Goldstone et al., 2014)

Reminder: You should not switch drugs or stop your current treatment unless your doctor recommends it

The main ipamorelin side effect is increased appetite and weight gain, including fat gain