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Casagrande S, Bonetto V, Fratelli M, Gianazza E, Eberini I, Massignan T, Salmona M, Chang G, Holmgren A, Ghezzi P (2002) Glutathionylation of human thioredoxin: a possible crosstalk between the glutathione and thioredoxin systems

TG2 also catalyzes the incorporation of polyamines, including putrescine, spermidine, and spermine, into the glutamine residues of proteins to produce polyaminated proteins 3

Do we need supplemental glutathione

This process is particularly important within the liver, where glutathione contributes to Phase II detoxification pathways and helps protect cells from oxidative injury during normal metabolic activity