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To determine whether the signals share the same causal variant, we applied co-localization analysis 17 and found that the signals co-localize with high probability (BMI % versus nausea, H4 = 96.6%

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Wird die erfindungsgeme wasserlsliche Zusammensetzung in eine wssrige Lsung zur Verabreichung bergefhrt, sollte die Konzentration des pharmazeutisch wirksamen Peptidsalzes in der Lsung vorzugsweise etwa 0,0000001 bis 10% (Gew./Vol.), mehr bevorzugt etwa 0,000001 bis 5% (Gew./Vol.) oder besonders bevorzugt etwa 0,00001 bis 1% (Gew./Vol.) betragen