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demonstrated that ACSL4 knockdown resulted in higher levels of free oxidized PUFAs, decreased oxidized membrane phospholipids, and reduced cell death [21]

Gene Expression ECM Remodeling Copper Signaling Mechanism of Action Primary TGF- / Collagen / LOX Extracellular Matrix Remodeling GHK-Cu upregulates collagen I, collagen III, and decorin synthesis in fibroblast cultures

Since numerous molecules share these signaling pathways, the identification of key molecules is crucial to achieve favorable consequences in cancer therapy

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