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It involves the coordinated interaction of multiple biological processes, including: Cell migration to the site of injury Formation of new blood vessels (angiogenesis) Fibroblast activation Extracellular matrix remodeling Regulation of the inflammatory response Cytoskeletal organization For this reason, research is increasingly focused on combining peptides that possess distinct yet complementary mechanisms of action

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Quantification was conducted in QuPath software, with cell detection algorithms identifying DAPI-positive nuclei co-expressing c-Fos

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