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Only one patient had a high enough elevation for a short-chain acyl-CoA dehydrogenase defect to be considered

Overall, faced with diversified molecular platforms and delivery methods, R&D teams and regulatory agencies should consider DMPK as a core element throughout drug development decision-making: with rigorous in vitro and in vivo data chains and existing tools, precisely identifying and managing DDI and special population risks to ensure the clinical efficacy and safety of innovative drugs

However, all of these compounds also show inflammatory effects (Vollmar et al., 2008