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Okunogbe, Nugent, Spencer)

Retatrutide is a triple GIP/GLP-1/glucagon agonist

Regulation of glucagon and glucagon-like peptide-1 receptor messenger ribonucleic acid expression in cultured rat pancreatic islets by glucose, cyclic adenosine 3',5'-monophosphate, and glucocorticoids

In addition, an increased number of dead cells as a function of time was detected in kidney, liver, and ileum tissue, reflected by a terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) staining (Fig