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This article will explore the clinical rationale behind the 7.2 mg dose, analyze the STEP UP trial data, and examine the emerging debate around ultra-potent dosing

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Weeks 1-4: 2.5 mg once weekly Weeks 58 : 5 mg once weekly Weeks 912 : 7.5 mg once weekly if you can tolerate the previous dosage and further glycemic control is needed Weeks 1316 : 10 mg once weekly, if you have still not reached your target blood sugar levels Weeks 1720 : 12.5 mg once weekly, if needed Week 20 and onwards : 15 mg once weekly, which is the maximum dosage of Mounjaro If you experience side effects, your doctor may delay dosage escalation for the next 4 weeks or lower the dosage of Mounajro

The modest sample size and short treatment duration limited the study, according to investigators