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Investigators describe it as the first triple-agonist peptide to advance to Phase 3 in any indication

These studies report increased abundance of bacterial groups including Negativicutes , Christensenellaceae , Selenomonadales , and Ruminococcus , alongside a notable decrease in Verrucomicrobia , Akkermansia muciniphila , and Erysipelotrichaceae UCG003 showed an decrease (Liu et al., 2023)