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Importantly, increased levels of SOA and H 2 O 2 in both studies were associated with depletion of enzymatic antioxidants such as superoxide dismutase (SOD) catalase (CAT), glutathione reductase (GR) and glutathione peroxidase (GPx) as well as decreased expression of all examined antioxidant genes (GPx, GR, SOD and CAT) [8, 9]

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Proper sterile technique involves alcohol swabbing injection sites, using new needles for each administration, and avoiding contamination of vial contents