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(PubMed) de Koning EJ, van der Zwaluw NL, van Wijngaarden JP, et al

Overexpression of ARHGAP6, which inhibits these pathways, results in increased CHAC1 expression, thereby promoting ferroptosis and inhibiting tumor growth

Exclusion criteria: Patients with acute viral hepatitis, immune hepatitis, Wilson disease , concurrent conditions in which free radical production is elevated like other inflammatory processes outside the liver or intake of antioxidant drugs affecting free radical scavenging such as vitamin C, A and E at time of biopsy

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