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In vitro drug sensitivity analyses have demonstrated that the overexpression of miRNA-15b or miRNA-16 can sensitize the SGC-7901/VCR cell line against anticancer drugs, whereas the downregulation of these miRNAs using antisense oligonucleotides confers MDR in the SGC-7901 cell line

iii ) as it has been known for a long time, diet and food intake affect renal gluconeogenesis and water balance ( KO mice likely stems from complex, age-dependent and long-term functional interactions between the brain, pancreatic islets, kidneys and intestines as well as other tissues where NKCC2 may be expressed, even in minimal quantities relative to the kidneys

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